The victory was a third in a row for the Gold Rush (9-1).
Wanto Joseph had 14 points and a season-high-tying eight assists for Xavier, and Denzell Erves had 11 points and a career-high-tying four blocked shots. Joseph and Erves have scored in double figures in every game this season.
Kwame Beard made five 3-pointers and scored 21 points for Mobile (4-2). Chris Richardson scored 14 points, and Dominick Brumfield had 10 points and 12 rebounds.
Mobile never caught Xavier after Simmons scored the first two points. The Gold Rush led 35-29 at halftime an extended the lead to 48-38 before the Rams closed the margin to 60-59 with 2:40 remaining.
A Xavier turnover in the final 10 seconds gave Mobile a chance to force overtime, but Chris Richardson missed a 3-pointer with three seconds remaining, and Xavier's Gary Smith rebounded.
Xavier committed a season-low nine turnovers and outshot the Rams 49 to 44.2 percent from the floor and outrebounded them 33-27. Mobile dominated on the perimeter, making 11-of-24 3-pointers to Xavier's 0-of-8. But the Gold Rush outscored the Rams 19-9 on free throws.
Xavier has won 30 of its past 32 non-conference home games and 49-of-52. It's the sixth time in Dannton Jackson's 10 seasons as head coach that the Gold Rush started 9-1 or better.
Xavier's next game will start at 7:30 p.m. Dec. 5 against city rival Loyola at the Convocation Center. It will be the final Gold Rush home game of the fall semester.
Box score
By Ed Cassiere, SID
XULAATHLETICS
XAVIER UNIVERSITY OF LOUISIANA